Q 32E - Organic Chemistry (Mcmurry)

Question

Question: Give an mRNA sequence that will code for the synthesis of angiotensin II

Asp-Arg-Val-Tyr-Ile-His-Pro-Phe

Step-by-Step Solution

Answer

The mRNA sequence that will code for the synthesis of angiotensin II

Asp-Arg-Val-Tyr-Ile-His-Pro-Phe

Possible codon assignments according to the base triplet for the given mRNA sequence are:

Asp	Arg	Val	Tyr	Ile	His	Pro	Phe
GAU	CGU	GUU	UAU	AUU	CAU	CCU	UUU
GAC	CGC	GUC	UAC	AUC	CAC	CCC	UUC
	CGA	GUA		AUA		CCA
	CGG	GUG				CCG

Step 1: Definition of mRNA sequence

A sequence used as a template to assemble in order the chain of amino acids that form a protein is defined as an mRNA sequence.

Step 2: Explanations

The codon message for Asp can be GAU and GAC, 

For Arg, it can be CGU, CGC, CGA, and CGG

For Val, the message will be GUU, GUC, GUA, and UUC

For Tyr, it can be UAU and UAC

For Ile it can be AUU, AUC and AUA

For His message will be CAU and CAC

For Pro, it will be CCU, CCC, CCA, and CCG

Lastly, for Phe, it would be coded as UUU and UUC.

There can be many codes for the given amino acid-base sequence.