Q 31E - Organic Chemistry (Mcmurry)

Question

Question: Give an mRNA sequence that will code for the synthesis of mentenkephalin.

Tyr-Gly-Gly-Phe-Met

Step-by-Step Solution

Answer

The mRNA sequence that will code for the synthesis of metenkephalin

Tyr-Gly-Gly-Phe-Met

Codon sequence

Possible codon assignments according to the base triplet for the given mRNA sequence are 

Tyr	Gly	Gly	Phe	Met
UAU	GGU	GGU	UUU	AUG
UAC	GGC	GGC	UUC
	GGA	GGA
	GGG	GGG

 

In total, there could be 64 mRNA sequences possible.

Step 1: Definition of mRNA sequence

A sequence used as a template to assemble in order the chain of amino acids that form a protein is defined as an mRNA sequence

Step 2: Explanations

The codon message for Tyr can be UAU and UAC.

For Gly, it can be GGU, GGC, GGA, and GGG

Similarly, Phe, the message will be UUU and UUC. 

For Met, it would code as AUG.

There can be many codes for the given amino acid-base sequence.