Q 30E - Organic Chemistry (Mcmurry)

Question

Question: Draw the complete structure of the deoxyribonucleotide sequence from which the mRNA codon in problem 28-29 was transcribed.

Step-by-Step Solution

Answer

The structure of the deoxyribonucleotide sequence from which (5’)-UAC-(3’) was transcribed is:

The base sequence in the original DNA strand can be obtained as:

mRNA strand

(5’)-UAC-(3’)

The antisense DNA strand will be the complement of mRNA:

Antisense DNA

(3’)-ATG - (5’)

Step 1: Definition of DNA Sequence

An mRNA sequence is defined as a sequence used as a template to assemble in order the chain of amino acids that form a protein.

Step 2: Explanation

In the given mRNA, (5’)-UAC-(3’) is transcribed from the deoxyribonucleotide (antisense DNA).

(3’)-ATG - (5’) are linked together with phosphodiester bonds. In the structure of UAC ribonucleotide, the phosphodiester can be seen between G and T and between T and A.

The antisense DNA strand that gives rise to mRNA sequence (5’)-UAC-(3’) is (3’)-ATG - (5’).