Q21-74E - Organic Chemistry (Mcmurry)

Question

21-74 Tranexamic acid, a drug useful against blood clotting, is prepared commercially from p-methylbenzonitrile. Formulate the steps likely to beused in the synthesis. (Don't worry about cis-trans isomers; heating to300 °C interconverts the isomers.)

Step-by-Step Solution

Answer

Step 1: Introduction to the Concept

Chemical synthesis is the method of reworking a reactant or beginning material into a product or many products through appearing one or greater chemical reactions.

Step 2: Solution Explanation

The benzene ring and nucleophilic acyl substitution reduction were employed to make tranexamic acid.