Q21-73E - Organic Chemistry (Mcmurry)

Question

21-73 N,N-Diethyl-m-toluamide (DEET) is the active ingredient in manyinsect repellent preparations. How might you synthesize this substancefrom m-bromotoluene?

Step-by-Step Solution

Answer

The importance of nucleophile acyl substitution in drug production is demonstrated.

Step 1: Introduction to the Concept

Chemical synthesis is the method of reworking a reactant or beginning material into a product or many products through appearing one or greater chemical reactions.

Step 2: Solution Explanation

The process involves employing$SOC{l}_2$ to change the leaving group â€"OH to a better leaving group via nucleophile acyl substitution.