Q. 17.64 - An Introduction to General, Organic, and Biological Chemistry

Question

How is protein synthesis affected if the normal base sequence $CCC$ in the DNA template strand is changed to $ACC$? 

Step-by-Step Solution

Answer

 If normal base sequence $CCC$ is changed to $ACC$ then the amino acid sequence is altered.

Step 1: Given Information

We need to explain how protein synthesis affected if the normal base sequence $CCC$ in the DNA template strand is changed to $ACC$.

Step 2: Explanation

The typical triplet $CCC$ creates the glycine-coding codon $GGG$. Codon $UGG$, which codes for tryptophan, is formed via the mutation $ACC$. As a result, the amino acid sequence is altered.