Q. 17.61 - An Introduction to General, Organic, and Biological Chemistry

Question

What is the effect of a deletion mutation on the amino acid sequence of a polypeptide? 

Step-by-Step Solution

Answer

If one of the bases of DNA is deleted than all the bases are shifted down one and the polypeptide chain is significantly exclusive due to the fact each institution after the deletion is now exclusive. 

Step 1: Given Information

We need to explain the effect of a deletion mutation on the amino acid sequence of a polypeptide 

Step 2: Explanation

Reading DNA base sequences in groups of three results in polypeptide chains.

Deletion mutation on the amino acid sequence of a polypeptide effects in two ways:

1. If one of the DNA bases is deleted, all of the bases are pushed down one position, and the polypeptide chain is drastically altered because each group after the deletion is now distinct. 
2. If you delete an entire group, it has less of an impact, and in certain cases, no impact at all, depending on how significant the group was.