Q. 17.13 - An Introduction to General, Organic, and Biological Chemistry

Question

In Lesch-Nyhan syndrome, a deficiency of the enzyme guanine transferase causes an overproduction of uric acid. Draw the condensed structural formula for guanosine monophosphate.

Step-by-Step Solution

Answer

The condensed structural formula for guanosine monophosphate is drawn

Step 1 : Introduction

The objective is to draw the condensed structure of guanosine monophosphate 

Step 2 : Explanation

Nucleic acids are organic macromolecules that are present all over the cell. They were first discovered in the nuclei of cells. Nucleic acids, such as DNA and RNA, are found in all known forms of life. 

One of the components of nucleotide structure is nitrogen bases. Purines and pyrimidines are nitrogen bases that form various nucleotide structures.

Step 3 : Explanation

Guanosine monophosphate - it is a nucleotide present in RNA which contains nitrogen base Guanine ($\mathrm{G}$), a five-carbon ribose sugar unit, and a phosphate group.

The nitrogen atom present in the nitrogen base is connected by $\mathrm{N}$ - glycosidic bond to the carbon $1$ of the ribose sugar and the carbon $5$ of the sugar forms an ester linkage with the phosphate group.