Q. 17.12 - An Introduction to General, Organic, and Biological Chemistry

Question

In the genetic disease uridine monophosphate synthase deficiency, symptoms include anemia, cardiac malformations, and infections. Draw the condensed structural formula for uridine monophosphate.

Step-by-Step Solution

Answer

The condensed formula for uridine monophosphate is identified and drawn

Step 1 : Introduction

The objective is to draw the condensed structure of uridine monophosphate 

Step 2 : Explanation

Nucleic acids are organic macromolecules that are present all over the cell. They were first discovered in the nuclei of cells. Nucleic acids, such as DNA and RNA, are found in all known forms of life. 

One of the components of nucleotide structure is nitrogen bases. Purines and pyrimidines are nitrogen bases that form various nucleotide structures.

Step 3 : Explanation

Uridine monophosphate ($\mathrm{UMP}$) is a nucleotide that contains the nitrogen base Uracil ($\mathrm{U}$), a five-carbon ribose sugar unit, and a phosphate group. It is found in RNA.

The nitrogen atom in the nitrogen base creates an $\mathrm{N}$ -glycosidic connection with carbon $1$ of the ribose sugar, while the sugar's carbon $5$ forms an ester bond with the phosphate group.