Chapter 28

Which one of the following statements is not true? [Main Sep. 06, 2020 (II)] (a) Lactose contains \(\alpha\)-glycosidic linkage between \(\mathrm{C}_{1}\) of galactose and \(\mathrm{C}_{4}\) of glucose. (b) Lactose is a reducing sugar and it gives Fehling's test. (c) Lactose \(\left(\mathrm{C}_{11} \mathrm{H}_{22} \mathrm{O}_{11}\right)\) is a disaccharide and it contains 8 hydroxyl groups. (d) On acid hydrolysis, lactose gives one molecule of \(\mathrm{D}(+)\)-glucose and one molecule of D(+)-galactose

Which of the following is not an essential amino acid? [Main Sep. \(\mathbf{0 5}, \mathbf{2 0 2 0}\) (I)] (a) Tyrosine (b) Leucine (c) Valine (d) Lysine

Which of the following statements is not true about RNA? [Main April 12, 2019 (I)] (a) It controls the synthesis of protein. (b) It has always double stranded helix structure. (c) It usually does not replicate. (d) It is present in the nucleus of the cell.

Consider the following reactions: [Main Sep. 02, 2020 (I)] (i) Glucose \(+\mathrm{ROH} \stackrel{\text { dry } \mathrm{HCl}}{\longrightarrow}\) Acetal \(\frac{x \text { eq. of }}{\left(\mathrm{CH}_{3} \mathrm{CO}\right)_{2} \mathrm{O}}\) acetyl derivative (ii) Glucose \(\stackrel{\mathrm{Ni} / \mathrm{H}_{2}}{\longrightarrow} \mathrm{A} \frac{y \text { eq. of }}{\left(\mathrm{CH}_{3} \mathrm{CO}\right)_{2} \mathrm{O}}\) acetyl derivative (iii) Glucose \(\frac{z \text { eq. of }}{\left(\mathrm{CH}_{3} \mathrm{CO}\right)_{2} \mathrm{O}}\) acetyl derivative ' \(x^{\prime}, y^{\prime}\) and ' \(z^{\prime}\) in these reactions are respectively. (a) \(5,4 \& 5\) (b) \(4,6 \& 5\) (c) \(4,5 \& 5\) (d) \(5,6 \& 5\)

Among the following compounds most basic amino acid is: (a) Asparagine (b) Lysine (c) Serine (d) Histidine

Thiol group is present in : (a) Cysteine (b) Methionine (c) Cytosine (d) Cystine

Which of the following statement is not true for glucose? [Main Jan. 08, 2020 (I)] (a) Glucose exists in two crystalline forms \(\square\) and \(\square\) (b) Glucose gives Schiff's test for aldehyde (c) Glucose reacts with hydroxylamine to form oxime The pentaacetate of glucose does not (d) react with hydroxylamine to give oxime

The correct structure of histidine in a strongly acidic solution \((\mathrm{pH}=\) 2) is :

Which of the vitamins given below is water soluble? (a) Vitamin E (b) Vitamin \(\mathrm{K}\) (c) Vitamin \(\mathrm{C}\) (d) Vitamin D

Two monomers in maltose are: (a) \(\square-\mathrm{D}\)-glucose and \(\square-\mathrm{D}\)-glucose (b) \(\square-\) D-glucose and \(\square-\) D-galactose (c) \(\square-\mathrm{D}\)-glucose and \(\square-\mathrm{D}\)-fructose (d) \(\square-\) D-glucose and \(\square-\) D-glucose

Which one of the following bases is not present in DNA? (a) Quinoline (b) Adenine \(\quad\) [Main 2014] (c) Cytosine (d) Thymine

Which of the following statements is correct? [Main Jan. 07, 2020 (II)] (a) Gluconic acid can form cyclic (acetal/hemiacetal) structure (b) Gluconic acid is a dicarboxylic acid (c) Gluconic acid is a partial oxidation product of glucose (d) Gluconic acid is obtained by oxidation of glucose with \(\mathrm{HNO}_{3}\)

The reason for double helical structure of DNA is the operation of: [Main Online April 19, 2014] (a) Electrostatic attractions (b) van der Waals forces (c) Dipole - Dipole interactions (d) Hydrogen bonding

Which of the given statements is INCORRECT about glycogen? (a) It is a straight chain polymer similar to amylose. (b) Only a-linkages are present in the molecule. (c) It is present in animal cells. (d) It is present in some yeast and fungi.

Among the following vitamins the one whose deficiency causes rickets (bone deficiency) is [Main Online April 25, 2013] (a) Vitamin A (b) Vitamin B (c) Vitamin D (d) Vitamin \(\mathrm{C}\)

Amylopectin is composed of : (a) \(\square-\mathrm{D}\)-glucose, \(\mathrm{C}_{1}-\mathrm{C}_{4}\) and \(\mathrm{C}_{1}-\mathrm{C}_{6}\) linkages (b) \(\beta\)-D-glucose, \(\mathrm{C}_{1}-\mathrm{C}_{4}\) and \(\mathrm{C}_{2}-\mathrm{C}_{6}\) linkages (c) \(\beta\)-D-glucose, \(\mathrm{C}_{1}-\mathrm{C}_{4}\) and \(\mathrm{C}_{1}-\mathrm{C}_{6}\) linkages (d) \(\square\)-D-glucose, \(\mathrm{C}_{1}-\mathrm{C}_{4}\) and \(\mathrm{C}_{2}-\mathrm{C}_{6}\) linkages

Among the following, the essential amino acid is : [Main Online April 8, 2017] (a) Alanine (b) Valine (c) Aspartic acid

Number of stereo centers present in linear and cyclic structures of glucose are respectively: [Main April 10, 2019 (II)] (a) \(5 \& 4\) (b) \(4 \& 4\) (c) \(5 \& 5\) (d) \(4 \& 5\)

Observation of "Ruhemann's purple" is a confirmatory test for the presence of [Main Online April 10, 2016] (a) Starch (b) Reducing sugar (c) Protein (d) Cupric ion

Which of the following enzyme converts starch into maltose? [Main Online April 9, 2013] (a) Diastase (b) Maltase (c) Zymase (d) Invertase

Which of the following statements is not true about sucrose? [Main April 9, 2019 (I)] (a) It is a non reducing sugar (b) The glycosidic linkage is present between \(\mathrm{C}_{1}\) of \(\alpha\)-glucose and \(\mathrm{C}\) of \(\beta-\) fructose (c) It is also named as invert sugar (d) On hydrolysis, it produces glucose and fructose

Glycosidic linkage is actually an : (a) Carbonyl bond (b) Ether bond (c) Ester bond (d) Amide bond

Match the following: (i) Riboflavin (a) Beriberi (ii) Thiamine (b) Scurvy (iii) Pyridoxine (c) Cheilosis (iv) Ascorbic acid (d) Convulsions (a) (i) \(-(\mathrm{a})\), (ii) \(-(\mathrm{d})\), (iii) \(-(\mathrm{c})\), (iv) \(-(\mathrm{b})\) (b) (i) \(-(\mathrm{c})\), (ii) \(-(\mathrm{d})\), (iii) \(-(\mathrm{a})\), (iv) \(-(\mathrm{b})\) (c) (i) \(-(\mathrm{c})\), (ii) \(-(\mathrm{a}),(\mathrm{iii})-(\mathrm{d})\), (iv) \(-(\mathrm{b})\) (d) (i) \(-(\mathrm{d})\), (ii) \(-(\mathrm{b})\), (iii) \(-(\mathrm{a})\), (iv) \(-(\mathrm{c})\)

Glucose on prolonged heating with HI gives : (a) \(n\)-Hexane (b) 1 - Hexene (c) Hexanoic acid (d) 6-iodohexanal

Among the following, the incorrect statement is: [Main Online April 16, 2018] (a) Cellulose and amylose have 1,4 -glycosidic linkage (b) Lactose contains \(\beta\)-D-galactose and \(\beta\)-D-glucose (c) Maltose and lactose have 1,4 -glycosidic linkage (d) Sucrose and amylose have 1,2 -glycosidic linkage

The number of chiral centres present in threonine is

The number of \(\lambda C=O\) groups present in a tripeptide Asp - Glu Lys is

The incorrect statement among the following is : [Main Online April 9, 2017] (a) \(\alpha\)-D-glucose and \(\beta\)-D-glucose are anomers. (b) \(\alpha\)-D-glucose and \(\beta\)-D-glucose are enantiomers. (c) Cellulose is a straight chain polysaccharide made up of only \(\beta\)-Dglucose units. (d) The penta acetate of glucose does not react with hydroxyl amine.

Accumulation of which of the following molecules in the muscles occurs as a result of vigorous exercise? (a) Glycogen (b) Glucose (c) Pyruvic acid (d) L-lactic acid

Complete hydrolysis of starch gives : (a) glucose only [Main Online April 10, 2015] (b) galactose and fructose in equimolar amounts (c) glucose and galactose in equimolar amounts (d) glucose and fructose in equimolar amounts

A tetrapeptide has \(-\mathrm{COOH}\) group on alanine. This produces glycine (Gly), valine (Val), phenyl alanine (Phe) and alanine (Ala), on complete hydrolysis. For this tetrapeptide, the number of possible sequences (primary structures) with \(-\mathrm{NH}_{2}\) group attached to a chiral center is

Which of the following will not show mutarotation? [Main Online April 12, 2014] (a) Maltose (b) Lactose (c) Glucose (d) Sucrose

The substituents \(\mathrm{R}_{1}\) and \(\mathrm{R}_{2}\) for nine peptides are listed in the table given below. How many of these peptides are positively charged at \(\mathrm{pH}\) \(=7.0 ?\) $$ \begin{array}{|c|c|c|} \hline \text { Peptide } & \mathbf{R}_{\mathbf{1}} & \mathbf{R}_{\mathbf{2}} \\\ \hline \text { I } & \mathrm{H} & \mathrm{H} \\ \hline \text { II } & \mathrm{H} & \mathrm{CH}_{3} \\ \hline \text { III } & \mathrm{CII}_{2} \mathrm{COOII} & \text { II } \\ \hline \text { IV } & \mathrm{CH}_{2} \mathrm{CONH}_{2} & \left(\mathrm{CH}_{2}\right)_{4} \mathrm{NH}_{2} \\ \hline \text { V } & \mathrm{CH}_{2} \mathrm{CONH}_{2} & \mathrm{CH}_{2} \mathrm{CONH}_{2} \\ \hline \text { VI } & \left(\mathrm{CH}_{2}\right)_{4} \mathrm{NH}_{2} & \left(\mathrm{CH}_{2}\right)_{4} \mathrm{NH}_{2} \\ \hline \text { VII } & \mathrm{CH}_{2} \mathrm{COOH} & \mathrm{CH}_{2} \mathrm{CONH}_{2} \\ \hline \text { VIII } & \mathrm{CH}_{2} \mathrm{OH} & \left(\mathrm{CH}_{2}\right)_{4} \mathrm{NH}_{2} \\ \hline \text { IX } & \left(\mathrm{CII}_{2}\right)_{4} \mathrm{NII}_{2} & \mathrm{CII}_{3} \\ \hline \end{array} $$

Synthesis of each molecule of glucose in photosynthesis involves : [Main 2013] (a) 18 molecules of ATP (b) 10 molecules of ATP (c) 8 molecules of ATP (d) 6 molecules of ATP

A decapeptide (Mol. wt. 796) on complete hydrolysis gives glycine (Mol. wt. 75), alanine and phenylalanine. Glycine contributes \(47.0 \%\) to the total weight of the hydrolysed products. The number of glycine units present in the decapeptide is

Which of the following statement is not correct? [Main Online April 25, 2013] (a) Amylopectin is a branched polymer of \(\alpha\)-glucose. (b) Cellulose is a linear polymer of \(\beta\)-glucose (c) Glycogen is the food reserve of plants (d) All proteins are polymers of \(\alpha\)-amino acids.

The total number of basic groups in the following form of lysine is \([2010]\) NCCCCC(N)C(=O)[O-]

Following two amino acids lysine and glutamine form dipeptide linkage. What are two possible dipeptides?

Which of the following statements is not true about RNA? [Main April 12, 2019 (I)] (a) It controls the synthesis of protein. (b) It has always double stranded helix structure. (c) It usually does not replicate. (d) It is present in the nucleus of the cell.

The two forms of D-glucopyranose obtained from the solution of D-glucose are called [2005S] (a) Isomers (b) Anomers (c) Epimers (d) Enantiomers

The pair of compounds in which both the compounds give positive test with Tollen's reagent is [2004S] (a) Glucose and Sucrose (b) Fructose and Sucrose (c) Acetophenone and Hexanal (d) Glucose and Fructose

The number of chiral carbons present in sucrose is

Which of the following statement(s) is (are) true? [Adv. 2019] (a) Oxidation of glucose with bromine water gives glutamic acid. (b) Hydrolysis of sucrose gives dextrorotatory glucose and laevorotatory fructose. (c) The two six-membered cyclic hemiacetal forms of \(\mathrm{D}-(+)\) - glucose are called anomers. (d) Monosaccharides cannot be hydrolysed to give poly-hydroxy aldehydes and ketones

Match the following, choosing one item from column \(\mathbf{X}\) and the appropriate item from column \(\mathrm{Y}\). [1983 - 2 Marks] (i) Lucas test (a) Phenol (ii) Neutral \(\mathrm{FeCl}_{3}\) test (b) Glucose (iii) Dye test (c) Tertiary alcohol (iv) Tollen's test (d) Aniline

This question contains Statement-1 (Assertion) and Statement-2 (Reason) and has 4 choices (a), (b), (c) and (d) out of which ONLY ONE is correct. Statement-1 : Glucose gives a reddish-brown precipitate with Fehling's solution. because Statement-2 : Reaction of glucose with Fehling's solution give \(\mathrm{CuO}\) and gluconic acid. [2007] (a) Statement-1 is True, Statement- 2 is True; Statement-2 is a correct explanation for Statement-1 (b) Statement-1 is True, Statement- 2 is True; Statement-2 is not a correct explanation for Statement-1 (c) Statement-1 is True, Statement- 2 is False (d) Statement- 1 is False, Statement- 2 is True.

The Fisher projection of D-glucose is drawn below. [2004 - 2 Marks] OCC(O)C(O)C(O)CO (i) Draw the Fisher projection of \(L\)-glucose. (ii) Give the reaction of L-glucose with Tollen's reagent