Q39E - Organic Chemistry (Mcmurry) | StudyQuestionHub

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Q39E

Question

The Darzens reaction involves a two-step, base-catalyzed condensation of ethyl chloroacetate with a ketone to yield an epoxy ester. The first step is a carbonyl condensation reaction, and the second step is an S_N2 reaction. Write both steps, and show their mechanisms.

Step-by-Step Solution

Verified

Answer

The product is formed by carbonyl reaction followed by $S_{N} 2$ reaction.

1Reaction:

The given reaction is,

2Mechanism

The mechanism for the above reaction is as follows,

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