Q29-30E - Organic Chemistry (Mcmurry)

Question

Question: Draw the complete structure of the deoxyribonucleotide sequence from which the mRNA codon in Problem 28-29 was transcribed

Step-by-Step Solution

Answer

The structure of DNA sequence from the mRNA codon transcribed is,

Step 1: Introduction

Nucleotides are linked together to form biopolymers, which are lengthy chains of nucleotides. Each nucleotide is made up of a phosphate group and a nucleoside. An aldopentose sugar is connected to a nitrogen atom of a heterocyclic purine or pyrimidine base through its anomeric carbon.

Step 2: Structure of ribonucleotide codon UAC

The UAC codon assignment is provided to mRNA.

The deoxyribonucleotide $5^{\text{'}}-\text{UAC}-3^{\text{'}}$  is transcribed from the supplied mRNA (antisense DNA). i.e.$3^{\text{'}}\text{-ATG-}{5}^{\text{'}}$are joined by phosphodiester bonds. The phosphodiester between G and T, T and A may be observed in the structure of UAC ribonucleotide.

The structure of the deoxyribonucleotide sequence from $5^{\text{'}}\text{-UAC-}{3}^{\text{'}}$ is

The base sequence from the original DNA can be obtained as,

In the mRNA strand,${\mathbf{5}}^{\mathbf{\text{'}}}\mathbf{\text{-UAC-}}{\mathbf{3}}^{\mathbf{\text{'}}}$ . The antisense DNA strand will be the complement of mRNA.

In the antisense DNA,${\mathbf{3}}^{\mathbf{\text{'}}}\mathbf{\text{-ATG-}}{\mathbf{5}}^{\mathbf{\text{'}}}$ .