Q28-19E
Question
One of the steps in the metabolic degradation of guanine in hydrolysis to give xanthine. Propose a mechanism.
Step-by-Step Solution
Verified Answer
The mechanism for the hydrolysis of guanine is
1Definition of mechanism
The sequence of elementary steps by which a chemical reaction occurs is defined as a mechanism.
2Explanations
The hydrolysis of guanine occurs by the catalytic guanine deaminase and occurs when water reacts according to the nucleophilic addition reaction. Water gets added according to the nucleophilic addition reaction to the CN bond.
This is followed by the removal of ammonia by a substitution reaction.
The hydrolysis of guanine gives rise to xanthine
The mechanism for the hydrolysis of guanine is,
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