Q14P
Question
What product would you expect from the following reaction?
Step-by-Step Solution
Verified Answer
The product is formed when diethyl 4-methyl heptane dioate is
Ethyl 4-methyl 2-oxocyclohexanecarboxylate.
1The given reaction followed the Dieckmann cyclization:
In which Intramolecular Claisen condensations can be carried out with diesters, just as intramolecular aldol condensations can be carried out with diketones.
This reaction works best on 1,6-diesters and 1,7-diesters.
2Cyclization of 1,7-diesters in the presence of N a + - O E t , and H 3 O +
diethyl 4-methyl heptane dioate Ethyl 4-methyl 2-oxocyclohexanecarboxylate
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