Q. 18.30 - An Introduction to General, Organic, and Biological Chemistry

Question

What coenzymes are needed for the oxidation of pyruvate to $\mathrm{acetyl} \mathrm{CoA}$?

Step-by-Step Solution

Answer

The coenzymes needed for the oxidation of pyruvate to $\mathrm{acetyl} \mathrm{CoA}$ are ${\mathrm{NAD}}^{+}$ and coenzyme $\mathrm{A}$

Step 1: Given information

We need to find the coenzymes for the oxidation of pyruvate to $\mathrm{acetyl} \mathrm{CoA}$

Step 2: Explanation

We know that

The ${\mathrm{NAD}}^{+}$ and Coenzyme $\mathrm{A}$ are required for the conversion of pyruvate to $\mathrm{acetyl} \mathrm{CoA}$. Pyruvate dehydrogenase, an enzyme that catalyzes this reaction in aerobic conditions, aids this process.