Chapter 18
Clinical Chemistry · 12 exercises
Problem 1
Extreme copper deficiency is seen in what fatal condition? a. Menkes' disease b. Klinefelter's syndrome c. Meese disease d. Kayser-Fleischer rings
4 step solution
Problem 2
Suppose the controller on a GFAAS is defective and the furnace is running cold. What effect will this likely have on the number of photons absorbed in the measurements? a. It will decrease the number of photons absorbed. b. It will increase the number of photons absorbed. c. It will have little effect. d. It is not a relevant question because AAS relies on emission of light from electronically excited atoms.
5 step solution
Problem 3
Why would a clinical chemist develop an arsenic method that combines liquid chromatography with ICP-MS? a. To separate and quantitate several different arsenic-containing species in the same sample b. To eliminate interference by sodium from the analysis c. To shorten the run time of the measurement d. To lower the coefficient of variation for total arsenic measurements
6 step solution
Problem 4
Select the answer that designates three techniques widely used for elemental analysis, identified according to the initials for the techniques. a. AAS, ICP-MS, AES b. NMR, ICP-MS, AES c. GC-MS, ICP-MS, AES d. HPLC-ICP-MS, AAS, FTIR
4 step solution
Problem 5
One of the calcium isotopes \(\left({ }^{40} \mathrm{Ca}\right)\) has an atomic weight of \(40 .\) At what positions in a mass spectrum would singly and doubly charged ions of this isotope of calcium appear? Assume that singly charged Ca is listed first. a. 40 and 20 b. 40 and 60 c. 40 and 80 d. 40 and 40
4 step solution
Problem 6
What primary purposes does the torch serve in ICP-MS? a. Vaporization, atomization, and ionization b. Vaporization, atomization, and electronic excitation c. Nebulization, atomization, and photon absorption d. Droplet transport, vaporization, and ion detection
4 step solution
Problem 7
Manganese toxicity resembles the following disease: a. Parkinson's disease b. Wilson's disease c. Alzheimer's disease d. Menkes' disease
4 step solution
Problem 8
Iron is physiologically active only in the ferrous form in a. Hemoglobin b. Cytochromes c. Ferritin d. Transferrin
5 step solution
Problem 9
A metal ion required for optimal enzyme activity is best termed a(an) a. Cofactor b. Accelerator c. Coenzyme d. Catalyst
4 step solution
Problem 10
Which trace metal is contained in glucose tolerance factor? a. Chromium b. Copper c. Selenium d. Zinc
3 step solution
Problem 11
What metal may be used as a treatment for Wilson's disease? a. Zinc b. Copper c. Molybdenum d. Fluorine
4 step solution
Problem 12
The metal ion essential for the activity of xanthine oxidase and xanthine dehydrogenase is a. Molybdenum b. Iron c. Zinc d. Manganese
3 step solution