Chapter 20

Which antiepileptic agent gained wider therapeutic use also to treat trigeminal neuralgia and the manic phase of bipolar disorder? (A) ethosuximide (B) zonisamide (C) levetiracetam (D) carbamazepine (E) phenytoin

Which one of the following agents is considered the drug of choice for initial treatment of generalized absence seizure (petit mal) in children? (A) ethosuximide (B) zonisamide (C) levetiracetam (D) carbamazepine (E) phenytoin

Topiramate has which set of three mechanisms of action? (A) increases \(\mathrm{Na}^{+}\)channel inactivation, increases GABA, blocks glutamate (B) decreases \(\mathrm{Na}^{+}\)channel inactivation, decreases GABA, blocks glutamate (C) increases \(\mathrm{Ca}^{2+}\) channel inactivation, increases GABA, blocks glutamate (D) decreases \(\mathrm{Ca}^{2+}\) channel inactivation, increases GABA, blocks glutamate (E) decreases \(\mathrm{Ca}^{2+}\) channel flow, increases GABA, blocks glutamate

Gabapentin has which mechanism of action? (A) inhibits monoamine oxidase (B) has an agonist effect at dopamine receptors (C) increases \(\mathrm{Na}^{+}\)channel inactivation (D) blocks reuptake of neurotransmitters (E) increases release of neurotransmitters.