Chapter 10
Brenner and Stevens’ Pharmacology · 5 exercises
Problem 1
A patient with type 2 diabetes and hypertension has recently developed proteinuria. Which drug would be most likely to slow the progression of renal disease in this patient beyond its ability to lower blood pressure? (A) metoprolol (B) enalapril (C) nifedipine (D) lisinopril (E) diltiazem
4 step solution
Problem 2
A man with a history of poor dental hygiene and high blood pressure complains of tender and swollen gums during an appointment with his dentist. Which antihypertensive drug might be contributing to this condition? (A) irbesartan (B) metoprolol (C) nifedipine (D) hydrochlorothiazide (E) doxazosin
4 step solution
Problem 3
Which drug binds to renin and inhibits its activity? (A) aliskiren (B) atenolol (C) enalapril (D) hydrochlorothiazide (E) valsartan
3 step solution
Problem 4
What is the mechanism by which irbesartan lowers blood pressure? (A) inhibiting renin (B) blocking angiotensin AT1 receptors (C) decreasing calcium entry into smooth muscle (D) inhibiting formation of angiotensin II (E) antagonizing aldosterone
3 step solution
Problem 5
Which drug blocks \(\alpha\) - and \(\beta\)-adrenoceptors, and also has antioxidant and other beneficial effects? (A) carvedilol (B) amlodipine (C) propranolol (D) hydrochlorothiazide (E) doxazosin
3 step solution