Chapter 25

Read the dosage information or label given for the following problems. Express body weight conversion to the nearest tenth where indicated and dosages to the nearest tenth. Furadantin oral suspension \(25 \mathrm{mg}\) p.o. qoh is ordered for a child weighing 37.4 lb. Recommended dosage is \(5-7 \mathrm{mg} / \mathrm{kg} / 24\) hr divided qoh. Available: Furadantin oral suspension \(25 \mathrm{mg}\) per \(5 \mathrm{~mL}\). a. What is the child's weight in kilograms to the nearest tenth? b. What is the dosage range for this child? c. Is the dosage ordered safe? (Prove mathematically.) d. How many milliliters must be given per dosage to administer the ordered dosage? Calculate the dose if the order is safe.

Read the dosage information or label given for the following problems. Express body weight conversion to the nearest tenth where indicated and dosages to the nearest tenth. Keflex (cephalexin) suspension \(250 \mathrm{mg}\) p.o. qoh is ordered for a child weighing \(66 \mathrm{lb}\). The usual pediatric dosage is 25 to \(50 \mathrm{mg} / \mathrm{kg} /\) day in four divided dosages. Available: Keflex suspension \(250 \mathrm{mg}\) per \(5 \mathrm{~mL}\) a. Is the dosage ordered safe? (Prove mathematically.) b. How many milliliters would you need to administer one dosage? Calculate the dose if the order is safe.

Read the dosage information or label given for the following problems. Express body weight conversion to the nearest tenth where indicated and dosages to the nearest tenth. Streptomycin sulfate \(400 \mathrm{mg}\) IM daily is ordered for a child weighing \(35 \mathrm{~kg}\). The recommended dosage is 20 to \(40 \mathrm{mg} / \mathrm{kg} /\) day once daily. a. Is the dosage ordered safe? (Prove mathematically.) b. A \(1-g\) vial of streptomycin sulfate is available in powdered form with the following instructions: Dilution with \(1.8 \mathrm{~mL}\) of sterile water will yield \(400 \mathrm{mg}\) per \(\mathrm{mL}\). How many milliliters will you need to administer the ordered dosage? Calculate the dosage if the order is safe.

Read the dosage information or label given for the following problems. Express body weight conversion to the nearest tenth where indicated and dosages to the nearest tenth. A child weighing 46 lb has an order for ranitidine (Zantac) \(20 \mathrm{mg}\) IV \(\mathrm{q} 8 \mathrm{~h}\). Is the dosage ordered safe? (Prove mathematically.) Available: Pediatric Use: While limited data exist on the administration of IV ranitidine to children, the recommended dose in pediatric patients is for a total daily dose of 2 to \(4 \mathrm{mg} / \mathrm{kg},\) to be divided and administered every 6 to 8 hours, up to a maximum of 50 mg given every 6 to 8 hours. This recommendation is derived from adult clinical studies and pharmacokinetic data in pediatric patients. Limited data in neonatal patients (less than one month of age) receiving ECMO have shown that a dose of \(2 \mathrm{mg} / \mathrm{kg}\) is usually sufficient to increase gastric \(\mathrm{pH}\) to \(>4\) for at least 15 hours. Therefore, doses of \(2 \mathrm{mg} / \mathrm{kg}\) given every 12 to 24 hours or as a continuous infusion should be considered.

Read the dosage information or label given for the following problems. Express body weight conversion to the nearest tenth where indicated and dosages to the nearest tenth. The recommended dosage for neonates receiving ceftazidime (Tazidime) is \(30 \mathrm{mg} / \mathrm{kg}\) q \(12 \mathrm{~h}\). The neonate weighs \(3,500 \mathrm{~g}\). a. What is the neonate's weight in kilograms to the nearest tenth? b. What is the safe dosage for this neonate?

Read the dosage information or label given for the following problems. Express body weight conversion to the nearest tenth where indicated and dosages to the nearest tenth. The recommended dosage for Mithracin for the treatment of testicular tumors is 25 to \(30 \mathrm{mcg} / \mathrm{kg} .\) A client weighs \(190 \mathrm{lb}\). a. What is the client's weight in kilograms to the nearest tenth? b. What is the dosage range in milligrams for this client? (Round to the nearest tenth.)

Calculate the child's dosage in the following problems. Determine if the prescriber's order is correct. If the order is incorrect, give the correct dosage. Express answers to the nearest tenth. A child with a BSA of \(0.55 \mathrm{~m}^{2}\) has an order for \(5 \mathrm{mg}\) of a medication. The adult dosage is \(25 \mathrm{mg}\).

Using the formula method for calculating BSA, determine the BSA in the following clients, and express answers to the nearest hundredth. An adult who weighs \(60.9 \mathrm{~kg}\) and is \(130 \mathrm{~cm}\) tall

Calculate the dosages to be given. Use labels where provided. Order: Azidothymidine \(7 \mathrm{mg}\) p.o. qoh. Available: Azidothymidine \(10 \mathrm{mg}\) per mL

Calculate the dosages to be given. Use labels where provided. Order: Epivir \(150 \mathrm{mg}\) p.o. bi.d. Available: Epivir oral solution labeled \(10 \mathrm{mg}\) per mL

Calculate the dosages to be given. Use labels where provided. Order: Retrovir \(80 \mathrm{mg}\) p.o. \(\mathrm{q} 8 \mathrm{~h}\). Available: Retrovir syrup labeled \(50 \mathrm{mg}\) per \(5 \mathrm{~mL}\)

Calculate the dosages to be given. Use labels where provided. Order: Amoxicillin \(100 \mathrm{mg}\) p.o. ti.d. Available: Amoxicillin oral suspension labeled \(250 \mathrm{mg}\) per \(5 \mathrm{~mL}\)

Calculate the dosages below. Use the labels where provided. Calculate to the nearest hundredth where necessary. Order: Gentamicin \(7.3 \mathrm{mg}\) IM \(\mathrm{q} 12 \mathrm{~h}\). Available: \(20 \mathrm{mg}\) per \(2 \mathrm{~mL}\)

Calculate the dosages below. Use the labels where provided. Calculate to the nearest hundredth where necessary. Order: Atropine \(0.1 \mathrm{mg}\) subcut stat. Available: Atropine \(400 \mathrm{mcg}\) per mL

Calculate the dosages below. Use the labels where provided. Calculate to the nearest hundredth where necessary. Order: Ampicillin \(160 \mathrm{mg} \mathrm{IM}\) q \(12 \mathrm{~h}\). Available: Ampicillin \(250 \mathrm{mg}\) per mL

Calculate the dosages to be given. Round answers to the nearest tenth as indicated (express answers in milliliters). Order: Tylenol 0.4 g p.o. q4h p.r.n. for temp greater than \(101^{\circ} \mathrm{F}\). Available: Tylenol elixir labeled \(160 \mathrm{mg}\) per \(5 \mathrm{~mL}\)

Calculate the dosages to be given. Round answers to the nearest tenth as indicated (express answers in milliliters). Order: Clindamycin \(100 \mathrm{mg}\) IV q6h. Available: Clindamycin labeled \(150 \mathrm{mg}\) per \(\mathrm{mL}\)

Calculate the dosages to be given. Round answers to the nearest tenth as indicated (express answers in milliliters). Order: Procaine penicillin 150,000 units IM q12h. Available: Procaine penicillin 300,000 units per \(\mathrm{mL}\)

Calculate the dosages to be given. Round answers to the nearest tenth as indicated (express answers in milliliters). Order: Dilantin \(62.5 \mathrm{mg}\) p.o. b.i.d. Available: Dilantin oral suspension labeled \(125 \mathrm{mg}\) per \(5 \mathrm{~mL}\)

Calculate the dosages to be given. Round answers to the nearest tenth as indicated (express answers in milliliters). Order: Meperidine (Demerol) \(20 \mathrm{mg} \mathrm{IM}\) q 4h p.r.n. Available: Meperidine labeled \(25 \mathrm{mg}\) per mL

Calculate the dosages to be given. Round answers to the nearest tenth as indicated (express answers in milliliters). Order: Tetracycline \(250 \mathrm{mg}\) p.o. q6h. Available: Tetracycline oral suspension labeled \(125 \mathrm{mg}\) per \(5 \mathrm{~mL}\)

Calculate the dosages to be given. Round answers to the nearest tenth as indicated (express answers in milliliters). Order: Theophylline \(40 \mathrm{mg}\) p.o. q.i.d. Available: Theophylline elixir labeled \(80 \mathrm{mg}\) per \(15 \mathrm{~mL}\)

Calculate the dosages to be given. Round answers to the nearest tenth as indicated (express answers in milliliters). Order: Ferrous sulfate \(45 \mathrm{mg}\) p.o. every day. Available: Ferrous sulfate drops \(15 \mathrm{mg}\) per \(0.6 \mathrm{~mL}\)

Calculate the dosages to be given. Round answers to the nearest tenth as indicated (express answers in milliliters). Order: Famotidine \(20 \mathrm{mg}\) p.o. bi.d. Available: Famotidine \(8 \mathrm{mg}\) per mL.

Round weights and dosages to the nearest tenth as indicated. Order: Amprenavir \(650 \mathrm{mg}\) p.o. t.i.d. for a child weighing \(66 \mathrm{lb}\). The recommended dosage is \(22.5 \mathrm{mg} / \mathrm{kg}\) up to three times a day. Is the dosage ordered safe?

Round weights and dosages to the nearest tenth as indicated. Acetaminophen (Ofirmev) \(525 \mathrm{mg}\) IV \(\mathrm{q} 4 \mathrm{~h}\) is ordered for a child weighing \(92.4 \mathrm{lb}\). According to The Harriet Lane Handbook, the dosage for a child (age \(2-12\) years) or adolescent/adult weighing less than \(50 \mathrm{~kg}\) is \(15 \mathrm{mg} / \mathrm{kg} /\) dose \(\mathrm{q} 6 \mathrm{~h}\), or \(12.5 \mathrm{mg} / \mathrm{kg} /\) dose q4h IV up to a maximum of \(75 \mathrm{mg} / \mathrm{kg} / 24 \mathrm{hr}\). a. What is the safe dosage for this child? b. Is the dosage ordered safe?

Round weights and dosages to the nearest tenth as indicated. Order: Minoxidil for a child weighing 31 lb. The recommended dosage range is 0.25 to \(1 \mathrm{mg} / \mathrm{kg} / \mathrm{day}\) What is the safe dosage range for this child?

Determine the dosage in the following problems. Round dosages to the nearest tenth as indicated. The recommended dose for Oncovin (vincristine) is \(2 \mathrm{mg}\) per \(\mathrm{m}^{2}\). The child has a BSA of \(0.8 \mathrm{~m}^{2}\)

Determine the dosage in the following problems. Round dosages to the nearest tenth as indicated. The recommended dose for acyclovir is \(250 \mathrm{mg}\) per \(\mathrm{m}^{2}\). The child has a BSA of \(0.82 \mathrm{~m}^{2}\)

Determine the dosage in the following problems. Round dosages to the nearest tenth as indicated. The recommended dose for bleomycin in an adult with Hodgkin disease is 10 to 20 units per \(\mathrm{m}^{2}\). The adult has a BSA of \(1.83 \mathrm{~m}^{2}\). Give the dosage range.

Determine the flow rate in \(\mathrm{gtt} / \mathrm{min}\) for each IV using a microdrip, then indicate \(\mathrm{mL} / \mathrm{hr}\) for a controller. (Consider the medication volume as part of the total dilution volume as shown in the chapter.) A child is to receive 10 units of a medication. The dosage of 10 units is contained in \(1 \mathrm{~mL}\). Dilute to \(30 \mathrm{~mL},\) and infuse in 20 minutes. A \(15-\mathrm{mL}\) flush is to follow. Medication is placed in a burette. Determine the rate in: a. \(\mathrm{gtt} / \mathrm{min}\) b. \(\mathrm{mL} / \mathrm{hr}\)

Determine the flow rate in \(\mathrm{gtt} / \mathrm{min}\) for each IV using a microdrip, then indicate \(\mathrm{mL} / \mathrm{hr}\) for a controller. (Consider the medication volume as part of the total dilution volume as shown in the chapter.) A child is to receive \(80 \mathrm{mg}\) of a medication. The dosage of \(80 \mathrm{mg}\) is contained in \(2 \mathrm{~mL}\). Dilute to \(80 \mathrm{~mL},\) and infuse in 60 minutes. A \(15-\mathrm{mL}\) flush is to follow. Medication is placed in a burette. Determine the rate in: a. \(\mathrm{gtt} / \mathrm{min}\) b. \(\mathrm{mL} / \mathrm{hr}\)

Determine the normal dosage range for the following problems to the nearest tenth. State your course of action. A child weighing \(23 \mathrm{~kg}\) has an order for \(500 \mathrm{mg}\) of a medication in \(100 \mathrm{~mL}\) D5W q12h. The normal daily dosage range is 40 to \(50 \mathrm{mg} / \mathrm{kg}\). Determine if the dosage ordered is within normal range, and state your course of action.

Determine the normal dosage range for the following problems to the nearest tenth. State your course of action. A child weighing \(20 \mathrm{~kg}\) has an order for \(2 \mathrm{mg} \mathrm{IV}\) of a medication at \(10 \mathrm{AM}\) in \(100 \mathrm{~mL}\) D5W. The normal daily dosage is \(0.05 \mathrm{mg} / \mathrm{kg}\). Determine if the dosage ordered is within normal range, and state your course of action.

Determine the normal dosage range for the following problems to the nearest tenth. State your course of action. A child weighing \(15 \mathrm{~kg}\) has an order for \(55 \mathrm{mcg}\) of a medication \(\mathrm{IV}\) q \(12 \mathrm{~h}\). The dosage range is 6 to \(8 \mathrm{mcg} / \mathrm{kg} /\) day q12h. Determine if the dosage ordered is within normal range, and state your course of action.