Chapter 42

A woman is placed on fluconazole to treat renal candidiasis. Which pharmacologic property is associated with this drug? (A) poor oral bioavailability (B) low cerebrospinal fluid concentrations (C) primarily excreted in the urine (D) short elimination half-life (E) must be given parenterally

Which drug exerts a fungicidal effect by inhibiting synthesis of the fungal cell wall? (A) micafungin (B) posaconazole (C) flucytosine (D) nystatin (E) terbinafine

Which drug is most likely to cause drug interactions due to inhibition of human cytochrome P450 enzymes? (A) amphotericin B (B) fluconazole (C) caspofungin (D) naftifine (E) itraconazole

A child with tinea capitis is treated with griseofulvin. Which adverse effect most often results from taking this drug? (A) sedation (B) constipation (C) nausea and vomiting (D) blurred vision (E) headache and dizziness

Which infection is correctly treated with caspofungin? (A) pulmonary blastomycosis (B) invasive aspergillosis (C) systemic histoplasmosis (D) cryptococcal meningitis (E) mucormycosis