Chapter 36

Brenner and Stevens’ Pharmacology · 5 exercises

Problem 1

A 52-year-old postmenopausal woman is placed on a drug that decreases osteoclast activation but may cause hot flashes. Which drug was most likely given to this patient? (A) alendronate (B) denosumab (C) calcitonin (D) raloxifene (E) teriparatide

5 step solution

Problem 2

. A woman with osteolytic bone cancer is treated with a drug that reduces the serum calcium level. Which drug is indicated for this purpose? (A) calcitonin (B) ibandronate (C) calcitriol (D) zoledronic acid (E) cinacalcet

4 step solution

Problem 3

woman with a BMD T-score of -3 is given daily subcutaneous injections to increase bone formation. Which effect is most likely produced by this treatment? (A) increased absorption of dietary calcium (B) increased serum levels of vitamin D (C) decreased activation of osteoclasts (D) increased activation of osteoblasts (E) adsorption of the drug to bone

4 step solution

Problem 4

A man with bone pain and deformities is placed on a drug that increases cAMP levels in osteoclasts. Which beneficial effect may result from this treatment? (A) increased serum alkaline phosphatase activity (B) decreased urine hydroxyproline levels (C) increased bone turnover (D) increased serum calcium levels (E) increased osteoblast activity

4 step solution

Problem 5

A woman with osteoporosis is prescribed a drug that adsorbs to hydroxyapatite and remains in bone for years. Which drug is she most likely taking? (A) risedronate (B) teriparatide (C) calcitonin (D) denosumab (E) vitamin \(\mathrm{D}_3\)

3 step solution

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