Chapter 31
Brenner and Stevens’ Pharmacology · 5 exercises
Problem 1
Which drug is used to reduce the secretion of gonadotropins and gonadal steroids in children with precocious puberty? (A) cabergoline (B) menotropins (C) leuprolide (D) gonadorelin (E) octreotide
4 step solution
Problem 2
Which drug for treating acromegaly acts by blocking receptors for growth hormone? (A) pegvisomant (B) somatropin (C) octreotide (D) leuprolide (E) cabergoline
3 step solution
Problem 3
By which mechanism does cabergoline relieve symptoms of hyperprolactinemia in persons with a prolactin-secreting pituitary adenoma? (A) blocks prolactin receptors (B) blocks receptors for prolactin-releasing hormone (C) exerts a cytotoxic effect on pituitary adenoma cells (D) activates receptors for prolactin-inhibiting hormone (E) stimulates the breakdown of prolactin
3 step solution
Problem 4
Octreotide is correctly described by which of the following statements? (A) It is identical to naturally occurring somatostatin. (B) It is used to treat growth hormone deficiency. (C) It is administered orally. (D) It is a more potent inhibitor of growth hormone secretion than is somatostatin. (E) It contains more than 100 amino acids.
5 step solution
Problem 5
Which sequence of gonadotropin preparations is used to induce ovulation? (A) choriogonadotropin alfa then lutropin alfa (B) follitropin alfa then lutropin alfa (C) choriogonadotropin alfa then follitropin beta (D) chorionic gonadotropin (hCG) then lutropin alfa (E) follitropin alfa then follitropin beta
4 step solution