Chapter 17

A 66-year-old man with progressive fatigability and anorexia is found to have a low blood hemoglobin concentration, an elevated mean corpuscular volume, and an elevated serum concentration of methylmalonic acid.

Pegylation of a recombinant protein is employed for which purpose? (A) increasing oral bioavailability (B) decreasing renal excretion rate (C) increasing duration of action (D) increasing binding to receptors (E) reducing adverse effects