Chapter 15
Brenner and Stevens’ Pharmacology · 5 exercises
Problem 1
Which drug inhibits the intestinal absorption of cholesterol? (A) colesevelam (B) fenofibrate (C) ezetimibe (D) colestipol (E) niacin
3 step solution
Problem 2
A woman taking a drug for high LDL-cholesterol levels experiences muscle tenderness and pain with no apparent cause. Which agent is least likely to cause this adverse effect? (A) atorvastatin (B) niacin (C) fenofibrate (D) colestipol (E) rosuvastatin
4 step solution
Problem 3
What is the mechanism by which mipomersen lowers serum cholesterol levels? (A) inhibits microsomal triglyceride transport (B) inhibits cholesterol absorption (C) inhibits cholesterol biosynthesis (D) inhibits apolipoprotein B synthesis (E) increases cholesterol excretion
5 step solution
Problem 4
Stimulation of lipoprotein lipase by a fenofibrate results in lowered serum levels of which substance? (A) triglycerides (B) HDL-cholesterol (C) LDL-cholesterol (D) apolipoprotein B (E) phospholipids
4 step solution
Problem 5
Which drug increases the utilization of cholesterol to synthesize bile acids? (A) niacin (B) rosuvastatin (C) gemfibrozil (D) ezetimibe (E) colesevelam
4 step solution