Chapter 12

Inhibition of neprilysin leads to increased levels of which endogenous substance? (A) angiotensin II (B) natriuretic peptide (C) both angiotensin II and natriuretic peptide (D) neither angiotensin II or natriuretic peptide (E) nitric oxide

A man is brought to the emergency department complaining of nausea and vomiting, blurred and abnormally colored vision, and palpitations. Which drug is most likely responsible for these effects? (A) dobutamine (B) lisinopril (C) digoxin (D) milrinone (E) furosemide

Which drug has been demonstrated to increase survival in persons with heart failure? (A) furosemide (B) carvedilol (C) milrinone (D) digoxin (E) hydralazine-isosorbide dinitrate

Which mechanism is responsible for the cardiovascular effects of nesiritide? (A) inhibition of adenylyl cyclase (B) stimulation of adenylyl cyclase (C) inhibition of guanylyl cyclase (D) stimulation of guanylyl cyclase (E) inhibition of phosphodiesterase

Which drug blocks alpha-1, beta-1, and beta-2 adrenoceptors? (A) carvedilol (B) metoprolol (C) propranolol (D) dobutamine (E) phentolamine