Chapter 43

Components of the inflammatory response include all except: a. macrophages. b. neutrophils. c. B cells. d. mast cells. e. eosinophils.

When a person resists infection by a pathogen after being vaccinated against it, this is the result of: a.innate immunity. b.immunological memory. c. a response with defensins. d. an autoimmune reaction. e. an allergy.

One characteristic of a B cell is that it: a. has the same structure in both invertebrates and vertebrates. b. recognizes antigens held on class I MHC proteins. c. binds viral infected cells and directly kills them. d. makes many different BCRs on its surface. e. has a BCR on its surface, which is the IgM molecule.

Antibodies: a. are each composed of four heavy and four light chains. b. display a variable end, which determines the antibody's location in the body. c. belonging to the IgE group are the major antibody class in the blood. d. found in large numbers in the mucous membranes belong to class \(1 g\) G. e. function primarily to identify and bind antigens free in body fluids.

The generation of antibody diversity includes the: a. joining of \(\mathrm{V}\) to \(\mathrm{C}\) to \(\mathrm{J}\) segments to make a functional light chain gene. b. choice from several different types of C segments to make a functional light chain gene. c. deletion of the J segment to make a functional light chain gene. d. joining of \(V\) to \(J\) to \(C\) segments to make a functional light chain gene. e. initial generation of IgG followed later by IgM on a given cell.

\(\mathrm{An} \mathrm{APC}\) a. can be a CD8 \(^{+}\) T cell. b. derives from a phagocytic cell and is lymphocyte-stimulating. c. secretes antibodies. d. cannot be a B cell. e. cannot stimulate helper T cells.

Antibodies function to: a. deactivate the complement system. b. neutralize natural killer cells. c. clump bacteria and viruses for easy phagocytosis by macrophages. d. eliminate the chance for a secondary response. e. kill viruses inside of cells.

After Jen punctured her hand with a muddy nail, in the emergency room she received both a vaccine and someone else's antibodies against tetanus toxin. The immunity conferred here is: a. both active and passive. b. active only. c. passive only. d. first active; later passive. e. innate.

Medicine attempts to enhance the immune response when treating: a. organ transplant recipients. b. anaphylactic shock. c. rheumatoid arthritis. d. HIV infection. e. Type I diabetes.