Chapter 43

Compare and contrast the innate and adaptive immune systems.

List components of the innate immune system.

Describe how cells of the innate immune system recognize pathogens.

Explain how the four signs of inflammation relate to the changes that occur in the underlying tissues.

Describe how B cells produce a great variety of different antibodies, each specific for a particular antigen.

Explain how immunological memory is achieved.

Describe how positive and negative selection leads to a population of T cells that react to MHC molecules in association with nonself antigens, but not self antigens, and what happens when tolerance to self antigens is lost.

Describe three mechanisms that allow pathogens to evade the immune system.