Q8P
Question
Which of the following compounds can probably be prepared by a mixed aldol reaction? Show the reactants you would use in each case.
Step-by-Step Solution
Verified Answer
a. Yes,4-phenyl-3-buten-2-one can be prepared by a mixed aldol reaction, While ketone can undergo a self-condensation reaction
b. Yes, this compound can be prepared by mixed aldol condensation.
c. Yes, this compound will also be prepared by mixed aldol condensation.
1By using benzaldehyde and propanone we can easily get
4-phenyl-3-buten-2-one because benzaldehyde is a good nucleophiles accepter and does not have α-hydrogen hence it gives a mixed aldol reaction:
2By reaction between acetophenone and acetone:
3By reaction between cyclohexanone and propanal:
Other exercises in this chapter
Q23-6P
1-Butanol is prepared commercially by a route that begins with an aldol reaction. Show the steps that are likely to be involved.
View solution Q23-7P
Show how you would synthesize the following compound using an aldol reaction:
View solution Q23-8P
Which of the following compounds can probably be prepared by a mixed aldol reaction? Show the reactants you would use in each case.
View solution Q9P
Treatment of a 1,3-diketone such as 2,4-pentanedione with base does not give an aldol condensation product. Explain.
View solution