Q60E
Question
Ethyl dimethyl acetoacetate reacts instantly at room temperature when treated with ethoxide ion to yield two products, ethyl acetate, and ethyl 2-methyl propanoate. Propose a mechanism for this cleavage reaction.
Step-by-Step Solution
Verified Answer
The proper mechanism of cleavage reaction is mentioned below.
1Retro-Claisen condensation
Retro-Claisen condensation is a reverse reaction of Claisen condensation in which a 𝛃-keto ester on reacting with an excess of the strong base which causes the fragmentation of the compound into ester products.
2The mechanism:
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