Q51E
Question
Intramolecular aldol cyclization of 2,5-heptanedione with aqueous NaOH yields a mixture of two enone products in the approximate ratio 9;1. Write their structures, and show how each is formed.
Step-by-Step Solution
Verified Answer
Intramolecular aldol cyclization of 2,5-heptanedione with aqueous NaOH yields a mixture of two enone products in the approximate ratio 9;1 in which stable product is formed in major amount while less stable product formed in less amount.
1Formation of major and most stable product:
2Formation of minor and less stable product:
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