Q.31. - Organic Chemistry

Question

Question: Draw the product formed in each directed aldol reaction.

Step-by-Step Solution

Answer

Answer

Step 1: LDA

Lithium diisopropylamide (LDA) is a strong base with the molecular formula ${\left[{\left(C{H}_3\right)}_{2}CH\right]}_{\mathbf{2}}\mathit{N}\mathit{L}\mathit{i}$. In combination with ${\mathit{H}}_{\mathbf{2}}\mathit{O}$, it gives directed aldol reaction effectively.

Step 2: Cross-aldol reaction

The base abstracts the hydrogen ion $H^{+}$  from the enolizable aldehyde to initiate the reaction. 

Step 3: Product of the given reaction

a. The product of the given reaction is shown hereunder.

Product of a.

b. The product of the given reaction is shown hereunder.

Product of b.