Q30E
Question
In the Ritter reaction, an alkene reacts with a nitrile in the presence of strong aqueous sulfuric acid to yield an amide. Propose a mechanism.
Step-by-Step Solution
Verified Answer
A mechanism of Ritter reaction is shown below
1Step 1: Definition of mechanism
The sequence of elementary steps by which a chemical reaction occurs is defined as mechanism
2Step 2: Explanation
Protonation of the double bond in alkene by sulfuric acid leads to the formation of a tertiary carbocation.
The electrophilic nitrogen of the acetonitrile attacks the carbocation .
The nucleophilic attack of water on the nitrile carbon and subsequent removal of a proton yields the imidol.
The imidol then tautomerizes to yield the amide required
A mechanism of Ritter reaction is shown below
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