Q29-52E
Question
The primary fate of acetyl CoA under normal metabolic conditions is degradation in the citric acid cycle to yield CO2. When the body is stressed by prolonged starvation, however, acetyl CoA is converted into compounds called ketone bodies, which can be used by the brain as a temporary fuel. Fill in the missing information indicated by the four question marks in the following biochemical pathway for the synthesis of ketone bodies from acetyl CoA:
Step-by-Step Solution
Verified Answer
The complete equation for the ketone bodies synthesis can be determined.
1Step 1: Three ketone bodies
There are three ketone bodies are acetoacetate, acetone and D-B-hydoxybutyrate.
2Step 2: Reaction equation
The diagram can be represented as,
Other exercises in this chapter
Q29-44E
Why aren’t the glycolysis and gluconeogenesis pathways the exact reverse of each other?
View solution Q29-51E
In glycerol metabolism, the oxidation of sn-glycerol 3-phosphate to give dihydroxyacetone phosphate is catalyzed by sn-glycerol-3-phosphate dehydrogenase, with
View solution Q29-53E
The initial reaction in Problem 29-52, conversion of two molecules of acetyl CoA to one molecule of acetoacetyl CoA, is a Claisen reaction. Assuming that there
View solution Q29-54E
In step 6 of fatty-acid biosynthesis (Figure 29-5), acetoacetyl ACP is reduced stereospecifically by NADPH to yield an alcohol. Does hydride ion add to the Si f
View solution