Q29-10P - Organic Chemistry (Mcmurry)

Question

Which of the substances in the citric acid cycle are tricarboxylic acids, thus giving the cycle its alternative name?

Step-by-Step Solution

Answer

The Substances of the cycle is Citric and isocitrate.

Draw the Structure of Citrate and isocitrate

The Citric acid cycle is also known as the Tricarboxylic Acid cycle.

Therefore, That citrate and isocitrate anger the cycle its name is justified by their respective structures;

The Structure of Citrate and isocitrate.

To Given the Dehydration and rehydration of isocitrate

The Citric is isomerized by dehydration and rehydration of given isocitrate in step 2 of the TCA cycle.

Citrate both of these substances are produced as intermediate metabolites in the Kreb's TCA cycle and they contain three carboxylate anions CO₂^-.This Justifies the name tricarboxylic acid cycle given to this metabolic cycle.

Therefore, The Biochemical cycle of metabolism derives its name on the bars of its significant metabolites.