Q28-5P - Organic Chemistry (Mcmurry)

Question

What RNA base sequence is complementary to the following DNA base sequence?

(5’) GGCTAATCCGT (3’)

Step-by-Step Solution

Answer

The RNA base sequence which is complementary to the above DNA sequence can be written as $(3\text{'}) \mathrm{CUAAUGGCAU} (5\text{'})$.

Given Information

The DNA base sequence can be given as (5’) GGCTAATCCGT (3’).

Sense and antisense strand

The original DNA strand and complementary DNA strand can be denoted as,

$$\begin{gathered} (5\text{'}) \mathrm{GATTACCGTA} (3\text{'}) \\ (3\text{'}) \mathrm{CTAATGGCAT} (5\text{'}) \end{gathered}$$

The formation of RNA can be denoted as $(5\text{'}) \mathrm{GAUUACCGUA} (3\text{'})$. The formation of complementary RNA can be denoted as,

$(3\text{'}) \mathrm{CUAAUGGCAU} (5\text{'})$

The U can be replaced in T of DNA sense strand in RNA base sequence.