Q22P
Question
How would you prepare the following compound using a Robinson annulation reaction between a 𝛃-diketone and an𝛂, 𝛃 -unsaturated ketone? Draw the structures of both reactants and the intermediate Michael addition product
Step-by-Step Solution
Verified Answer
The given compound is formed by using the Michael addition reaction.
1Reaction
After analyzing the given compound, we find that this is a Michael addition reaction and the addition is taking place between two ketone compounds, and the formation of intermediate occurs as follows:
2After heating the compound, a water molecule is removed and desired product is formed:
Other exercises in this chapter
Q19P
What products would result after hydrolysis from the reaction of the enamine prepared from cyclopentanone and pyrrolidine with the following 𝛂-𝛃-uns
View solution Q23-20P
Show how you might use an enamine reaction to prepare each of the following compounds:
View solution Q23E
What ketones or aldehydes might the following enones have been prepared from by aldol reaction?
View solution Q24E
The following structure represents an intermediate formed by the addition of an ester enolate ion to a second ester molecule. Identify the reactant, the leaving
View solution