Q15.
Question
Question: What product is formed when each compound is treated first with LDA in THF solution at low temperature, followed by CH3CH2l ?
Step-by-Step Solution
Verified Answer
Answer
The products formed when each starting material is treated with LDA are shown below.
1Step 1: Definition of LDA
LDA is a strong base that abstracts protons from the least hindered site of the target molecule.
The attached isopropyl groups with the nitrogen atom make it bulky, and hence, they always act as a base. They withdraw protons from the least hindered source.
2Step 2: Given reactions
The products formed in each of the reactions are shown below.
Reaction a
Reaction b
Reaction c
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