Q. 56 E-c - Organic Chemistry (Mcmurry)

Question

Identify the indicated hydrogens in the following molecules as pro-R or pro-S:

Step-by-Step Solution

Answer

Step 5: Prochiral compounds

Prochiral compounds are planar compounds, and the carbon is hybridized, or they can be defined as achiral compounds that can be converted into chiral compounds by a single step.There are two terms, pro-R and pro-S, used in prochirality.

Step 6: Indicating hydrogens as pro-R and pro-S

(c).    

Suppose the indicated hydrogens attached to carbon are different—one is ${}^{\text{1}}\text{H}$, and the other is${}^2\text{H}$ If the chiral carbon configuration is R, the replaced hydrogen is pro-R. If the chiral carbon configuration is S, the replaced hydrogen is pro-S. The H below the plane is pro-R, and the H above the plane is pro-S.

Cysteine