Q. 18.72 - An Introduction to General, Organic, and Biological Chemistry

Question

Draw the condensed structural formulas for the products of the reaction of aspartate and $\alpha$-ketoglutarate, which is catalyzed by aspartate transaminase (AST).

Step-by-Step Solution

Answer

The products formed are Oxaloacetate and Glutamate.  

Oxaloacetate and Glutamate:  ${\mathrm{COOHCHNH}}_2{\left({\mathrm{CH}}_2\right)}_2{\mathrm{CONH}}_2$

Condensed structural formula of Oxaloacetate :  ${\mathrm{COOHCH}}_2\mathrm{COCOOH}$

Step 1: Given information

We need to draw the condensed structural formulas for the products of the reaction of aspartate and $\alpha$-ketoglutarate, which is catalyzed by aspartate  transaminase (AST). 

Step 2: Explanation

The reaction between aspartate and $\alpha$-ketoglutarate is as follows:-

The products formed are Oxaloacetate and Glutamate. 

Condensed structural formula of Glutamate:  ${\mathrm{COOHCHNH}}_2{\left({\mathrm{CH}}_2\right)}_2{\mathrm{CONH}}_2$

Condensed structural formula of Oxaloacetate :  ${\mathrm{COOHCH}}_2\mathrm{COCOOH}$