Problem 8

Question

You obtain an egg cell from the ovary of a white mouse and remove the nucleus from it. You then obtain a nucleus from a liver cell from an adult black mouse. You use the methods of nuclear transplantation to insert the nucleus into the empty egg. After some prompting, the new zygote divides into an early embryo, which you then implant into the uterus of a brown mouse. A few weeks later, a baby mouse is born. What color will it be? Why?

Step-by-Step Solution

Verified
Answer
The baby mouse will be black because the nucleus, which contains the genetic material, is from a black mouse.
1Step 1 - Understand the components
Identify the origins of the egg cell, nucleus, and uterus used in the process. The egg cell is from a white mouse, the nucleus is from a liver cell of a black mouse, and the uterus is from a brown mouse.
2Step 2 - Focus on the nucleus
Recognize that the nucleus contains the genetic material that will determine the baby mouse's characteristics. In this scenario, the nucleus is from a black mouse.
3Step 3 - Role of the cytoplasm
Observe that while the egg cell's cytoplasm comes from a white mouse, it does not contain genetic information that influences the color of the mouse.
4Step 4 - Implantation and development
Realize that the brown mouse's uterus merely provides an environment for the embryo to develop and does not impart any genetic traits to the baby mouse.
5Step 5 - Determine the outcome
Consider that the baby mouse will display the genetic traits dictated by the nucleus' genetic material. Since the nucleus came from a black mouse, the baby mouse will be black.

Key Concepts

genetic materialzygoteembryo developmentgenetic traits
genetic material
In all living organisms, genetic material is the DNA that contains the necessary information to build and maintain cells. This DNA is housed in the cell's nucleus.

When discussing nuclear transplantation, the genetic material from the donor nucleus is reprogrammed to direct the development of the recipient cell. This reprogramming defines the characteristics of the resulting organism. The transplanted nucleus in this exercise comes from an adult black mouse's liver cell.

This means all the DNA instructions to create the baby mouse's traits are from the black mouse, determining the baby mouse's appearance and other inherited traits.
zygote
A zygote is formed when an egg cell is fertilized by a sperm cell. It's the first step in the development of a new organism.

In nuclear transplantation, a zygote is artificially created by inserting a donor nucleus into an enucleated egg cell (an egg cell without its original nucleus). This zygote then begins the process of cell division and development.

In this exercise, the egg from the white mouse starts to divide after the black mouse's liver cell nucleus is inserted. It transforms into a new entity that carries the genetic makeup of the black mouse.
embryo development
Embryo development is a critical phase where the initial single cell (zygote) divides and differentiates into various cell types, eventually forming a whole organism.

In nuclear transplantation, once the new zygote with the donor nucleus begins to divide, it follows the same pathway as a naturally conceived embryo. This growth needs an environment to support it, which is usually the uterus.

Here, the brown mouse's uterus simply serves as a supportive host for the embryo to grow until birth. It does not contribute any genetic information to the developing embryo. This environment is crucial but does not alter the inherently determined characteristics by the nucleus.
genetic traits
Genetic traits are attributes and characteristics passed on from one generation to another through DNA. They can be physical traits like fur color or behavioral traits.

These traits are determined by the genetic material inside the nucleus of the cells. In the outlined exercise, since the nucleus came from a black mouse, the baby mouse inherits the black mouse's traits.

It's important to note that the genetic traits are not influenced by the cell's cytoplasm or the uterine environment in this process. This is why even though the egg cytoplasm came from a white mouse and the uterus belonged to a brown mouse, the baby mouse's color and other traits are dictated solely by the inserted nucleus from the black mouse.