Problem 3
Question
(a) The recommended daily allowance (RDA) of the trace metal magnesium is 410 \(\mathrm{mg} / \mathrm{day}\) for males. Express this quantity in \(\mu \mathrm{g} / \mathrm{day} .\) (b) For adults, the RDA of the amino acid lysine is 12 \(\mathrm{mg}\) per kg of body weight. How many grams per day should a 75 \(\mathrm{kg}\) adult receive? (c) A typical multivitamin tablet can contain 2.0 \(\mathrm{mg}\) of vitamin \(\mathrm{B}_{2}\) (riboflavin), and the RDA is 0.0030 \(\mathrm{g} / \mathrm{day} .\) How many such tablets should a person take each day to get the proper amount of this vitamin, assuming that he gets none from any other sources? (d) The RDA for the trace element selenium is 0.000070 \(\mathrm{g} /\) day. Express this dose in mg/day.
Step-by-Step Solution
VerifiedKey Concepts
Conversion of Units
For instance, when you need to convert milligrams to micrograms, you use the conversion factor: 1 mg equals 1000 µg. This is because 'micro' signifies a millionth ( 1/1,000,000), and 'milli' signifies a thousandth ( 1/1,000) of a base unit.
This means every milligram contains 1000 micrograms.
This conversion is essential in nutritional science since daily allowances are often listed in different units for precision or convenience.
For example, if the recommended dietary allowance (RDA) of magnesium is 410 mg/day, converting it to micrograms will give you:
- 410 mg/day × 1000 (µg/mg) = 410,000 µg/day
Recommended Dietary Allowance (RDA)
RDAs vary from nutrient to nutrient, and for any given nutrient, they can vary over different demographic parameters such as age or gender. They are guidelines set by health organizations to help individuals achieve good nutritional status.
For amino acids like lysine, the RDA is often expressed in relation to body weight, thus allowing for a more precise nutritional prescription.
For a 75 kg adult, if the RDA is 12 mg of lysine per kg, you simply multiply the body weight by this figure to determine how much lysine is needed daily:
- 12 mg/kg × 75 kg = 900 mg/day
- 900 mg/day × 1 g/1000 mg = 0.9 g/day
Trace Elements and Biochemistry
Selenium is one such trace element. Its RDA is 0.000070 g/day, which might seem minute, but its role in antioxidant enzymes and thyroid function is enormous. To make it easier to interpret, this can be converted into milligrams:
- 0.000070 g/day × 1000 mg/g = 0.070 mg/day
Vitamins, like riboflavin (Vitamin B2), have their RDA often listed in milligrams. In cases where someone must acquire their nutrients solely from supplements, calculating the number of tablets needed is crucial. If each tablet contains 2 mg of B2 and the RDA is 3.0 mg/day, two tablets ensure adequate intake by exceeding the half-tablet fraction:
- (3 mg/day ÷ 2 mg/tablet) = 1.5; taking 2 tablets ensures RDA is met.