PROBLEM 25.11 - Organic Chemistry

Question

What amine is formed by reduction of each amide?

a.

b.

c.

Step-by-Step Solution

Answer

Answer

a.

b.

c.

Amine and amide

Amine and amide are the nitrogen containing functional groups. The amine is represented as NH₂ and the amide is represented as CONH₂. 

Reduction of amide

The reduction of amide into amine is completed by the action of reagent lithium aluminum hydride LiAlH₄ . 

The gives hydrogen to the carbonyl carbon of amide and, therefore, it gives amine. 

Explanation

Primary ($1°$) , secondary ($2°$), and tertiary ($3°$) amides are reduced to$1°,2° \mathrm{and} 3°$amines, respectively using LiAlH₄ .

a. The given compound is primary amide; therefore, it gives primary amine as:

Conversion of amide a to amine

b. The given compound is tertiary amide; therefore, it gives tertiary amine as:

Conversion of amide b to amine

c.The given compound is secondary amide; therefore, it gives secondary amine as:

Conversion of amide c to amine