54E
Question
Fill in the reagents a–c that are missing from the following scheme:
Step-by-Step Solution
Verified Answer
The reagents are:
(a) NaOC2H5/CH3I
(b) H3O+/Heat ,and
(c) LDA/CH3I.
1Step 1: Acidic hydrogens in ketones
The alpha hydrogens in ketones are acidic in nature. The acidic protons will be removed in reaction with a strong base, and a carbanion intermediate will be formed. This carbanion intermediate on reaction with an alkyl halide forms a new C-C bond.
The given reaction is,
The given equation
2Step 2: Reagents
The reagents used in the reaction are,
The given chemical reaction
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52E
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